Supporting the continuation of the MND-SMART platform trial in the UK.
Principal Investigator: Dr Suvankar Pal
Lead Institution: University of Edinburgh
MND Association Funding: £500,000*
Funding dates: November 2023 - October 2028
*In partnership with MND Scotland
About the project
This project supports the continuation of the MND SMART clinical trial through helping to maintain the infrastructure surrounding the trial. MND-SMART, the UK’s first platform trial in MND, is a long-term study that is designed to test more than one potential treatment at a time. It is testing drugs that are already known to be safe and are approved for use to treat other conditions to see if they may be of benefit for people with MND. Researchers can change the drugs being tested throughout the trial, allowing new ones to be added and drugs that are found to have no benefit to be quickly removed. Trial participants taking one of the treatments will be compared with a group who receive a placebo (a dummy drug). Platform trials, like MND- SMART, that provide lasting infrastructure for trials and test several possible treatments at once may play a key role in finding effective therapies.
What could this mean for MND research?
This funding is helping to maintain the infrastructure of the trial so that it can continue for years to come and new drugs can be added for testing. This will give more people with MND the opportunity to take part in the trial now and in the future.
Resources
Take part in this research
This research study is currently recruiting participants. Click the button below to find out more about the study and if you are eligible to take part. Take part in the study
Project code: 110-950