Investigating whether home-based treatment using non-invasive ventilation could be more widely used for people living with MND.
Principal Investigator: Dr Dariusz Wozniak
Lead Institution: Royal Papworth Hospital (Cambridge)
MND Association Funding: £210,398*
Funding dates: March 2024 - August 2026
*Supported by the Oakdale Trust
About the project
People with MND who have breathing difficulties are offered a type of breathing support called Non-invasive ventilation (NIV). Typically, NIV is set up during a hospital visit and repeated visits to clinics are needed to monitor those with MND who use NIV. For some people, treatment may be able to be started and monitored at home, reducing the number of hospital visits needed. However, it is not yet known if home-based treatment is as safe and effective as hospital-based treatment. This trial will recruit 60 people with MND who need NIV and randomly assign them to either home-based or hospital-based treatment. The study will measure treatment effectiveness, patient and carer preferences, quality of life and cost effectiveness to assess whether home-based treatment may be more widely used for NIV for those with MND.
What could this mean for MND research?
The project could help to determine if using home-based treatment of non-invasive ventilation is a suitable approach for people living with MND. This would allow for a reduction in hospital visits which can be burdensome for people living with MND and their carers.
Project code: 944-794