Dissecting FUS’ cytoplasmic toxic gain-of-function in MND
TBC
- Research
Investigating mechanisms underlying the impaired hypoxia response in C9Orf72-related MND
Read about research we fund - Investigating how C9orf72 MND potentially causes nerve cells to no longer respond to oxygen deprivation and how this might lead…
- Research
Understanding the role of NEAT1 in energy metabolism in MND
Read about research we fund - Investigating the role of an RNA molecule called NEAT1 plays in MND.
- Research
Death of Rob Burrow CBE
Death of Rob Burrow CBE
Developing AAV-GRN gene therapy for MND
Find out more about research we fund: Developing AAV-GRN gene therapy for Motor Neuron Disease
- Research
Role of axonal transport in cell models carrying MND mutations
Find out more about research we fund: To establish whether axonal transport deficits in fast motor neurones are a general feature of MND, by comparing…
- Research
MIROCALS: Efficacy and safety of low-dose Interleukin-2
Read about research we fund - Testing whether Interleukin-2 could be a potential treatment for MND.
- Research
Home initiation and monitoring of non-invasive ventilation versus hospital-based care in people with MND
Read about research we fund - Investigating whether home-based treatment using non-invasive ventilation could be more widely used for people living with MND.
- Research
Tofersen given green light by the European Commission
Tofersen given green light by the European Commission for treating people with MND
- News
Investigating individualised effects of low-dose interleukin-2 throughout the MIROCALS Clinical Trial
Read about research we fund - Using RNA from the MIROCALS trial to understand the effect IL-2 antibody treatment has on the immune system.
- Research