Our aim is to provide people with MND the opportunity to take part in research studies. Below we list research projects that currently recruit participants for their study. These do not always involve testing a treatment (clinical trials). Most are focused on understanding the causes of MND, and improving diagnosis, care and quality of life of people affected by the disease.

To get notified about new research opportunities by email, you may wish to sign up to our MND Research list and newsletter. You can also find the clinical research projects taking place in the UK on the UK MND Clinical Studies Group website.

Take part in research areas

Treatment Trials

Tofersen

Recruiting people with asymptomatic SOD1-MND in Sheffield

MND SMART (platform trial)

Recruiting people with MND UK-Wide

ION363/Jacifusen

Recruiting people with FUS-ALS in London

MAGNET

Recruiting people with MND in London

Symptom Management

SETTLE: Investigating how to increase cough strength by improving "cough assist" devices

Recruiting people with MND around London

OptiCALS: A Randomised Controlled Trial to evaluate a nutritional management intervention

Recruiting people with MND and their carers UK-wide

Brain Computer Interfaces Patient Preference Survey

Recruiting people with MND UK-wide

Biomarker Studies

ALS Biomarker Study: Collecting biological samples to search for biomarkers

Recruiting people with MND, healthy controls and neurological controls in London

C9orf72 Cohort Study: Collecting biological samples to search for causes of C9orf72-MND

Recruiting people with MND, family members and healthy controls in Oxford

Improving wellbeing

TONiC: Examining the factors influencing qualify of life in neurological conditions

Recruiting people with MND UK-wide

Understanding the impact of a virtual peer support programme on wellbeing and caregiver burden

Recruiting peer supporters and carers UK-wide

Interviewing partners of people with MND about their experiences with co-parenting and support needs

Recruiting bereaved partners, family members/ carers of someone with MND who co-parented a minor during this time, UK-wide

Understanding how people with MND and carers feel about tests on thinking ability and behaviour in MND

Recruiting people with MND, family members and informal carers UK-wide

Investigating the use of video calls by palliative care organisations to provide emotional support

Recruiting people with MND, family members/carers and healthcare professionals in England

Artificial Intelligence and Augmentative Communication System design

Recruiting people with MND, family members/carers and healthcare professionals world-wide

Other Studies

MND Register: Collecting information about every person living with MND in England, Wales and Northern Ireland

Recruiting people with MND in England, Wales and Northern Ireland

Developing a stimulation-free remote motor unit number estimate (REMUNE) in MND

Recruiting people with MND, their carers and family members in London

Investigating the role of exercise in modifying neurodegeneration related to MND

Recruiting people with changes in C9orf72 and SOD1 genes world-wide

Sheffield MND Research Advisory Group

Recruiting people with MND, their carers and family members

Speech and Language Therapists' perspectives on voice and message banking for people with MND during the Covid-19 pandemic

Recruiting qualified speech and language therapists

Giving Voice to Experience: A Users’ History of Augmentative and Alternative Communication

Recruiting people with MND, their carers and family members who interact with communication aids